Tupi derived from the word "Tufi' meaning vine was chewed by the natives for its refreshing taste.
Once thickly cloaked with an untouched forest environd and tropical flora, the vast land of Tupi which owes its fertile soil to the volcanic waste that eroded from the orifice of the majestic Mt. Matutum, during the time when only the great B'laan tribes wandered any existed in covenant with the boundless resources of greenery and wildlife in the then Cotabato empire, has since time immemorial offered a great enticement to speculators and investors particularly in the field of agriculture.
In early 1936, the late Commonwealth President, Manuel L. Quezon, envisioned the development of Koronadal and Allah Valleys which at that time comprises the entirety of Cotabato Province. The move gave birth to the creation of the National Land Settlement Administration (NLSA) with the late Major General Paulino Santos as General Manager. The first settlers arrived as early as 1936 and pioneered in the development of Tupi under the forcible but humane administration of General Santos.
With the industry coupled with the patience and resolute determination of the pioneers, the then vast forest of Tupi was gradually transformed in a community of a unified citizenry and a flourishing area of agriculture where its unparalleled produced were the first time experienced by the settlers from the Luzon and Visayan Islands.
With the impact of development established in the then Barrio of Tupi, an Executive Order was signed by the President Elpidio Quirino numbered 612 which created Tupi into an independent municipality on September 11, 1953. With the creation of an independent municipality, the first set of appointed officials were inducted into office on October 2 of the same year. The same date was adopted as the municipality's foundation.
The major dialect in the municipality is Ilonggo, which is about 31.11% or 19,787 individuals. This is due to its proximity to Koronadal City which is an Ilonggo-dominated community. Cebuano and B'laan come next with 22.68% and 21.64% of the total population respectively. Other significant ethnic groups are Tagalog, Maguindanao, Aklanon, Ilocano, Kapampangan and Boholano.
It is bounded by the municipalities of Polomolok on the east; Koronadal on the west; Tampakan on the north; and Surallah on the south.
Primarily on agricultural area: major crops are pineapple, papaya, asparagus, fruits, vegetables, corn, coffee, bananas, cutflowers other High Value Commercial crops.
Considered as one of the best assets of Tupi is its mildly cool climate with an average of 23.94 degrees Celcius. It is coolest in January and warmest in March. Rainfall is evenly distributed throughout the year with heaviest fall in June. The municipality is not within the typhoon zone, hence calamity losses due to cyclones is not experienced in th locality except for heavy soil erosions caused by flash floods.